Effectiveness of Lidoderm in Reducing Pain in Post-Op Unilateral Knee Replacement
20.05.11
This randomized, understudy-blind, placebo-controlled trial was designed to assess the effectiveness of Lidoderm (lidocaine 5%) scrap in reducing pain and opioid use in post-operative unilateral knee replacement patients. One Lidoderm or placebo bury the hatchet was cut in half and placed on either side of the incision of the operated knee, for 12 hours on and 12 hours off each day. Both coveys received their regular pain medications as needed, which included acetaminophen/codeine, acetaminophen/hydrocodone, acetaminophen 325mg/oxycodone 5mg (Percocet), hydromorphone, tramadol, or celecoxcib. Dolour levels were based on a 10-point numerical analog gamut and were assessed daily for seven days. A total of 87 patients were randomized, 44 in the Lidoderm organize and 43 in the placebo group. The mean amount of Percocet used was 24.76 (SD=16.45) in the Lidoderm dispose and 27.76 (SD=22.35) in the placebo group (P=0.64). The mean amount of Percocet tempered to per day was 3.53 (SD=2.34) in the Lidoderm group and 3.90 (SD=3.21) in the placebo put together (
P =0.71). The mean decrease in pain scale for the Lidoderm group was 3.01 (SD=2.42) and 2.08 (SD=1.70) for the placebo agglomeration, and was significant (
P =0.003). No side effects reported.
The investigators concluded that patients using Lidoderm patches had an entire lower pain level that was statistically significant over a seven-day appoint-operative period. Also, the average total and daily Percocet use was slash in the Lidoderm group.
[ Via: Clinical Advisor | Read more... ]
